Pherecydes Pharma

PHAGOBURN project submission to the FP7 call: HEALTH.2013.2.3.1-1.

Pherecydes Pharma and its partners did submit the PHAGOBURN clinical trial project to the second selection step of the European call entitled: "Drugs and vaccines for infections that have developed or are at risk of developing significant anti-microbial resistance".

Pherecydes Pharma secures DGA funding for evaluating the use of bacteriophages on infected burns.

The French Government Defence procurement agency invests €900,000 towards Pherecydes Pharma managed €1.2-million project, involving several university and military laboratories.

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Pherecydes Pharma is developing bacteriophages (phages) to rapidly detect and/or kill a large range of bio threats, including antibiotic resistant, emergent or previously uncharacterized bacteria, as well as nosocomial infections to treat people and/or environments.

Pherecydes Pharma owns proprietary methods for accelerated targeted protein evolution, to built large phage banks or to engineer phages into targetable nano devices.

Bacteriophages

Bacteriophages are natural viruses: they can be found anywhere in our environment, our skin, in our intestinal tract, soil, water, etc.
They ONLY target bacteria
They are harmless to eukaryote organisms such as humans, animals, fishes, plants, insects, algae’s, etc.
They are highly specific toward a bacterial species and even to strains from that species
When they recognize their bacterial target, they attach to its outer membrane, inject their genetic material inside and reproduce in their host to make new phages that can get out and repeat the same cycle
The lytic phages, those we are interested in, kill properly the host bacteria as their progeny leave

Bacterial threats applications

Natural therapy to control human or animal bacterial infections (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus...)
Efficient treatment against bacteria that evolved resistance to antibiotics (examples of Gram négative resistance : BLSE; Gram positive resistance : MRSA...)
Diagnostic for industrial and medical applications
Biosecurity and biodefence to combat bioterrorism
Disinfection of surfaces, food products…

Bacteriophage reproduction

Download the reproduction cycle of lytic versus lysogenic phages

Infini'click : Web agency