Innovative biotechnologies: bacteriophages against infections

A new facility

Architecte : AIA LIFE DESIGNERS - Photos ©G.Satre

As part of the forthcoming installation of its bacteriophage GMP production site, Pherecydes Pharma opens a second facility in Nantes.

The facility is located 22 boulevard Benoni Goullin, in the Nantes Biotech business incubator on the Isle of Nantes.

Works, started in early September 2018, were completed at the end of March 2019.

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Last ressort treatment against Staphylococcus aureus

Local administration of a phage anti-staphylococcal mixture associated to antibiotics prevented the removal of a hip prosthesis, which would have led to a loss of mobility of the patient's leg.

With 20 months of relapse-free recurrence today, this treatment of last resort is considered a success.

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The European Union supports phage therapy

As part of its H2020 funding program for innovative companies, the European Commission (EC) is supporting Pherecydes Pharma to set up its PhagoPROD bacteriophage pharmaceutical production unit.

For that purpose EC has partnering with Julien Ménielle for the production of a YouTube video explaining phage therapy, as well as the research and production projects of Pherecydes Pharma.

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Salvage therapy

Four bacteriophages provided by Pherecydes Pharma to the Hospices Civils de Lyon have eliminated a bacterial infection induced by a Pseudomonas aeruginosa strain toto-resistant to antibiotics.

The description of this first case of compassionate treatment performed by Professor Tristan Ferry's team, in 2017, was published in the Journal of Antimicrobial in October 2018.

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Guy-Charles Fanneau de La Horie

Antibiotic resistance is a major health challenge in the years to come: 10 million people may die in 2050. New approaches are needed; Phage therapy represents the most promising hope. Pherecydes Pharma makes every effort to provide physicians and patients with effective treatments for the most serious bacterial infections.

Guy-Charles Fanneau de La Horie, Chief Executive Officer at Pherecydes Pharma



Magali Vidal-Engaurran

Pherecydes Pharma's project is to develop and produce drugs containing phages to offer a therapeutic alternative to antibiotic resistance. This development of pharmaceutical products goes side by side with the transformation of the company to become a pharmaceutical laboratory through the setup of its manufacturing site in Nantes. Quality issues are therefore at the heart of the transformation of Pherecydes Pharma.

Magali Vidal-Engaurran, Senior Pharmacist



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